תל חי

למעבדה במיגל בראשות פרופ' גיורא ריטבו דרוש/ה עוזר/ת מחקר לפרויקט העוסק בטכנולוגיית פירוק פוטוקטליטי של מזהמים במערכות מים ושפכים.

MigVax Ltd. a mid-stage startup company that develope vaccine to covid-19, is looking for a Research assistant – Assay development to join the Process Development Department.

Job Description:

Development of analytical, biological, and biochemical methods. Analytical support for the process development department. Scientific writing, protocols, reports, and procedures.

MigVax Ltd. a mid-stage startup company that develope vaccine to covid-19, is looking for an experianced QA/RA manager to join our team.

Responsibilities: Manage Quality Assurance and Regulatory Affairs on behalf of the company Develop regulatory strategy, prepare technical and submissions filings based on each country’s regulatory requirements. Manage the quality of the product and QMS, provide QA and regulatory guidance to company departments (Manufacturing, R&D, etc.), document control, manage the CAPA and MRB processes. Perform and oversee risk analysis, conduct internal-external and supplier audits, manage and participate in all quality processes in the company. writing and maintaining design controls and risk management processes Manage documentation control and training activities.

חברה המפתחת חיסון פומי כנגד COVID-19, מגייסת צוות מחקר מנוסה בניקוי והפקת חלבונים.

MigVax is developing an oral subunit vaccine for COVID-19. MigVax team has combined decades of track record with successful global vaccine and pharmaceutical achievements. Requirement: • Proficiency in Quality Assurance aspects of biological drug development o Knowledge of GMP-based requirements o Training of R&D teams in QA aspects, follow up on daily documentation and work performance o Design and establishment of a Controlled Documents Bank o Support writing of SOPs, working instructions, protocols etc for all experimental work; design of forms for experiment documentation o Design of qualification and validation of assays in collaboration with R&D team, support performance and report writing o Definition of QA requirements for equipment, follow up on calibration and maintenance o Good insights into Quality Control requirements for Biologics • Good understanding in Protein Biochemistry o Protein expression in different expression systems o Protein purification – SEC, Inversed Phase, affinity (Akta) o Protein analysis: ELISA, WB, impurities (HPLC) o Chemical analysis o Protein activity analysis: In vitro and cell-based assays

MigVax is developing an oral subunit vaccine for COVID-19. Humanity has never faced such a challenge - develop a vaccine within 18 months! MigVax team has combined decades of track record with successful global vaccine and pharmaceutical achievements. • Requirements Proficiency in Protein Biochemistry(hands on): o Protein expression in E coli, yeast, insect and/or mammalian cells o Protein purification – SEC, Inversed Phase, affinity (Akta) o Manufacturing process development o Protein analysis: ELISA, WB, impurities (HPLC) o Protein activity analysis: Cell-based assays development and performance, binding assays o Experience in assay qualification and validation is a great advantage o Knowledge of GMP-based documentation in an R&D environment • Experience in writing of quality documents: SOPs, protocols, research reports • Experience in the writing of the scientific part of CMC (under RA support) – big advantage • Team management experience is an advantage. • Subcontractors daily management and guidance/collaboration experience is an advantage.

MigVax is developing an oral subunit vaccine for COVID-19. Humanity has never faced such a challenge - develop a vaccine within 18 months! MigVax team has combined decades of track record with successful global vaccine and pharmaceutical achievements. • Requirements Proficiency in Protein Biochemistry(hands on): o Protein expression in E coli, yeast, insect and/or mammalian cells o Protein purification – SEC, Inversed Phase, affinity (Akta) o Manufacturing process development o Protein analysis: ELISA, WB, impurities (HPLC) o Protein activity analysis: Cell-based assays development and performance, binding assays o Experience in assay qualification and validation is a great advantage o Knowledge of GMP-based documentation in an R&D environment • Experience in writing of quality documents: SOPs, protocols, research reports • Experience in the writing of the scientific part of CMC (under RA support) – big advantage • Team management experience is an advantage. • Subcontractors daily management and guidance/collaboration experience is an advantage.

MigVax is developing an oral subunit vaccine for COVID-19. MigVax team has combined decades of track record with successful global vaccine and pharmaceutical achievements. Requirement: • Proficiency in Quality Assurance aspects of biological drug development o Knowledge of GMP-based requirements o Training of R&D teams in QA aspects, follow up on daily documentation and work performance o Design and establishment of a Controlled Documents Bank o Support writing of SOPs, working instructions, protocols etc for all experimental work; design of forms for experiment documentation o Design of qualification and validation of assays in collaboration with R&D team, support performance and report writing o Definition of QA requirements for equipment, follow up on calibration and maintenance o Good insights into Quality Control requirements for Biologics • Good understanding in Protein Biochemistry o Protein expression in different expression systems o Protein purification – SEC, Inversed Phase, affinity (Akta) o Protein analysis: ELISA, WB, impurities (HPLC) o Chemical analysis o Protein activity analysis: In vitro and cell-based assays

BMC is looking for a Site Reliability Engineer, who is passionate and self-motivated. Come join a dynamic group in BMC working on a next generation cloud-based solution for IT management.

In this role, you will be working with a team to maintain and evolve our Cloud native direction. The role drives business value through technical innovation such as simplification, extensibility, automation, and supportability. Responsibilities: Focus on Site Reliability Engineering (SRE) principles to develop tools, automation, dashboards to operationalize new BMC SaaS services and to transform BMC’s legacy applications to SaaS continuous delivery model. Collaborate with multiple teams within the company, including R&D, DevOps, Infrastructure, Support and Operations Help to deliver solutions for Cloud services – e.g. operationalizing new cloud services, Grafana dashboards, Kibana dashboards Automate and apply development principles to operational practice of SaaS management. Transform legacy technology to cloud native. Take part in evolve cloud observability to use industry standard tools, and coding. Conduct root cause analysis with the cross functional teams after service disruptions, identify opportunities for improvement, including development of such tools.

במסגרת התפקיד יהווה סמכות טכנית ויקבל אחריות הנדסית כוללת על מוצרים המיוצרים בחברה:

• העברה מפיתוח לייצור של מוצרים חדשים.
• מתן תמיכה הנדסית כוללת למוצרים שבאחריותו כולל ניהול שינויים לאורך כל חיי המוצר.
• עבודה שוטפת מול ממשקים רבים בפיתוח ובתפעול.
• עבודה מול לקוחות וספקים בארץ ובחו"ל.
• כתיבת ועדכון של הוראות עבודה
• הדרכה וליווי של הטכנאים בקווי הייצור.
• ניתוח ופתרון תקלות הנדסיות מורכבות.